Ivory Coast lost goalkeeper Boubacar Barry to injury in the first-half with the Elephants losing 1-0.
Barry, who had played in all four previous games at the tournament for Ivory Coast, was replaced by Stephan Loboue.
The 26-year-old Loboue plays for German second division side Greuther Furth and has not made a first-team appearance for his club this season.
Loboue's reactions to Egypt's second and third goals looked ponderous, but coach Gerard Gili insisted Barry's injury did not cost his team the game.
"The exit of my goalkeeper was not the reason we lost," said Gili.
"His absence only meant I lost a chance to make another substitution. We simply had an off day.
"We didn't expect to lose by such a wide margin but the Egyptians played well and pulled it off."