Steve Elworthy, tournament director of ICC World Twenty20 2009, said: "I am delighted that Trent Bridge joins Lord's and The Oval as a venue. It gives the tournament a good geographical spread without being logistically challenging for the players and officials."
More than 1.4 billion people were believed to have watched India beat Pakistan in the final of the inaugural World Twenty20 last year.
And Nottinghamshire chief executive Derek Brewer said the economic benefits to the area would be "incredible".
"It's a fantastic opportunity for us to showcase English cricket to the rest of the world," he told BBC Radio Nottingham.
"The figures are still being collated from the South Africa tournament last September but an estimated audience of around one billion people watched the final and 500 million people watched the semi-finals.
"As part of the package we will get the semi-final of the men's competition running alongside the semi-final of the women's competition so what fantastic coverage for the city, county and region."
Lancashire chief executive Jim Cumbes said he was not surprised that Trent Bridge was chosen ahead of Old Trafford.
"Following the first bidding process when Lord's and The Oval were successful, the ICC announced that the final venue would ideally need to be within 120 miles of these two grounds for logistical reasons," said Cumbes.
"Old Trafford did re-bid to be the third venue for the tournament, but we knew it would be a long shot considering the distance requirement between venues."